Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Sep;1(3):185-9.
doi: 10.1007/BF02042772.

Clinical relevance of antikeratin antibodies in rheumatoid arthritis

P Miossec, P Youinou, P Le Goff, M P Moineau

Clinical relevance of antikeratin antibodies in rheumatoid arthritis

P Miossec et al. Clin Rheumatol. 1982 Sep.

Abstract

Antikeratin antibodies (AKA) were found in 38 out of 96 patients with rheumatoid arthritis (RA); they appeared to be quite characteristic to this disease. There was a very low incidence of AKA positivity in the control groups, i.e., 1 out of 62 healthy subjects and 4 out of 158 other patients. With regard to the sensitivity of the test as a diagnostic tool, AKA was found to be weaker than the rheumatoid factor (RF) and the antiperinuclear factor (APF), whereas the specificity was much better than APF and RF. A clear correlation was shown between the titres of AKA and APF (p less than 0.001) and also between AKA levels and inflammation (p less than 0.02).

PubMed Disclaimer

References

    1. Scand J Rheumatol. 1979;8(1):1-9 - PubMed
    1. Ann Inst Pasteur (Paris). 1958 May;94(5):659-62 - PubMed
    1. Bull Rheum Dis. 1958 Dec;9(4):175-6 - PubMed
    1. Am J Med. 1956 Dec;21(6):888-92 - PubMed
    1. Br Med J. 1979 Jul 14;2(6182):97-9 - PubMed

Publication types

LinkOut - more resources