The kidney and strategies for the treatment of hypertension

Abstract

Renal compensatory mechanisms are a chief consideration when selecting an antihypertensive agent. The relationships, therefore, between renal blood flow and glomerular filtration rate, sodium handling by the kidney, and release of renin require particular attention. We shall examine therapeutic measures such as beta adrenergic blockers, vasodilators, calcium entry blockers, and converting enzyme inhibitors in light of their effects on renal blood flow.