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. 1983 Dec;7(6):769-74.

The number of polypeptide chains in the rod domain of bovine epidermal keratin

  • PMID: 6207830

The number of polypeptide chains in the rod domain of bovine epidermal keratin

E F Woods. Biochem Int. 1983 Dec.

Abstract

The physical properties of the alpha-helix enriched particle obtained by limited proteolysis of epidermal keratin have been examined. Molecular weights in benign and dissociating solvents, hydrodynamic measurements and chemical cross-linking experiments indicate that the particle has four polypeptide chains. It is proposed that the helical particle is assembled from a pair of two-stranded alpha-helical ropes.

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