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. 1978;9(1):1-7.
doi: 10.1159/000148915.

In situ assay of poxvirus-induced and virion-contained deoxyribonucleases in DNA polyacrylamide gels

E J Zöllner, R K Zahn, C Jungwirth

In situ assay of poxvirus-induced and virion-contained deoxyribonucleases in DNA polyacrylamide gels

E J Zöllner et al. Intervirology. 1978.

Abstract

Cowpox virus and vaccinia virus WR specific DNases were identified by an in situ assay using DNA-containing acrylamide gels. A DNase present in the isolated virions of strain cowpox and vaccinia WR was identified. Its properties as determined by the in situ assay resembled those of the well-characterized DNase V1. The assay was also used to follow the time course of 'acid' DNase induction by cowpox virus in primary chick embryo fibroblasts.

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