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. 1982 May;12(3):279-80.
doi: 10.1111/j.1365-2222.1982.tb02528.x.

An immunofluorescent study of the ampicillin rash

K C Gatter, J I Bell

An immunofluorescent study of the ampicillin rash

K C Gatter et al. Clin Allergy. 1982 May.

Abstract

The aetiology of the ampicillin rash is uncertain although numerous theories have been proposed--mainly immunological. One such concerns the presence of anti-epithelial antibodies which have received conflicting reports in the literature. In this study, skin biopsies from three patients with a maculopapular ampicillin-rash were studied by immunofluorescence to investigate the presence of anti-epithelial antibodies. However immunofluorescence for IgG, IgM, IgA and C3 was completely negative so that we were unable to provide any support for this particular hypothesis.

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