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Clinical Trial
. 1982 Aug;28(3):173-5.
doi: 10.1016/s0016-5107(82)73045-7.

The influence of carbon dioxide and nitrous oxide on pain during laparoscopy: a double-blind, controlled trial

G Minoli, V Terruzzi, G C Spinzi, C Benvenuti, A Rossini
Clinical Trial

The influence of carbon dioxide and nitrous oxide on pain during laparoscopy: a double-blind, controlled trial

G Minoli et al. Gastrointest Endosc. 1982 Aug.

Abstract

A prospective and controlled trial in 92 patients was done to determine the influence on the onset of pain during laparoscopy under local anesthesia by age, sex, perlaparoscopic guided liver biopsy, the presence of adhesions and of ascites, and the type of gas (CO2 or N2O) used in the abdominal cavity. N2O was found less pain provoking, while other factors had no influence on the onset of pain.

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