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. 1978 Jan;41(1):54-64.
doi: 10.1136/jnnp.41.1.54.

Refractory period studies in a human neuromuscular preparation

J Kopec, J Delbeke, A J McComas

Refractory period studies in a human neuromuscular preparation

J Kopec et al. J Neurol Neurosurg Psychiatry. 1978 Jan.

Abstract

A subtraction technique has been employed to study refractoriness in the median nerve and thenar muscles in man. The absolutely refractory periods of the distal motor nerve branches and of the muscle fibres were found to be similar, the majority being within the 2.5--3.0 ms range; the values were distributed in a unimodal manner. The relatively refractory periods of the motor nerve terminals were about 5 ms. In some experiments it was possible to record non-propagated potentials at the endplate zones of the muscle fibres.

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