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. 1982;10(1):25-36.
doi: 10.3109/03008208209034403.

Structure and assembly of the native collagen fibril

K A Piez

Structure and assembly of the native collagen fibril

K A Piez. Connect Tissue Res. 1982.

Abstract

Assembly in vitro of the native collagen fibril is a multistep process involving an initial intermediate of unknown structure, linear growth of thin filaments, lateral growth to form the fibril, and stabilization by covalent crosslinks. A model for the structure of the fibril is proposed consisting of a substructure of five-stranded microfibrils laterally compressed to place molecules in cross section on a near-hexagonal lattice.

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