Murine renal cell carcinoma: a suitable human model

Abstract

Many models of renal cell carcinoma are available. They have been observed in various species of animals. However, a renal adenocarcinoma which metastasizes, is available for study, and can be serially transplanted in BALB/c mice, appears to be the currently favored model. Our results reported herein describe a study on tumor kinetics, the effects of chemotherapy and other manipulations which appear relevant to the human state. A brief description of other available models is provided.