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. 1978 Feb;60(2):251-3.
doi: 10.1093/jnci/60.2.251.

Nitrosamine formation in human saliva

S R Tannenbaum, M C Archer, J S Wishnok, W W Bishop

Nitrosamine formation in human saliva

S R Tannenbaum et al. J Natl Cancer Inst. 1978 Feb.

Abstract

Nitrosamines formed when secondary amines were added to normal human saliva. Fractionation of saliva into cells and supernatant showed that factors that accelerated and retarded the nitrosation reaction were both present. Acidification of saliva greatly increased the nitrosamine yield, but differences in nitrosamine yield among saliva fractions were still observable.

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