[Does oxazepam (ADUMBRAN) interfere with anticoagulant treatment. A controlled study. (author's transl)]

Abstract

Newer communications dealing with drug interaction between tranquillizers and anticoagulants and the frequent combined intake of these drugs have induced us to perform a series of coagulation-and platelet parameters in 21 antiocoagulated patients with and without oxazepam (Adumbran). Control of adherence to the prescriptions was stressed upon: all cases were controlled by analysis of urin and nonadherent patients were excluded from statistical evaluation of hemostatic parameters. In the obtained well defined group no differences were observed in the effect of constant doses of anticoagulants and different tests of plasmatic coagulation and platelet aggregability.