[Influenza vaccination in dialysis patients]

Abstract

50 stabilized long-term hemodialysis patients were randomly selected to receive one intramuscular injection of a new influenza subunit vaccine containing only the surface antigens hemagglutinin and neuraminidase, or of an adjuvant containing whole virus vaccine. Both vaccines contained strains A/Victoria/3/75 and B/Hongkong/8/73. Both vaccines were very well tolerated and caused significant rises in the antibody titers within 4 weeks against both strains. The subunit vaccine produced significantly higher antibody titers against strain A than the whole virus vaccine.