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Comparative Study
. 1983 Aug;24(2):302-4.
doi: 10.1128/AAC.24.2.302.

Comparative activities of ciprofloxacin (Bay o 9867), norfloxacin, pipemidic acid, and nalidixic acid

H L Muytjens, J van der Ros-van de Repe, G van Veldhuizen
Comparative Study

Comparative activities of ciprofloxacin (Bay o 9867), norfloxacin, pipemidic acid, and nalidixic acid

H L Muytjens et al. Antimicrob Agents Chemother. 1983 Aug.

Abstract

An agar dilution method was used to measure the minimal inhibitory concentrations of ciprofloxacin (Bay o 9867), norfloxacin, pipemidic acid, and nalidixic acid against 496 clinical isolates. Ciprofloxacin and norfloxacin were active against all species tested (90% minimal inhibitory concentrations less than or equal to 8 micrograms/ml), although ciprofloxacin was somewhat more active, e.g., against gram-positive cocci. Pipemidic acid and nalidixic acid were active against most of the members of the Enterobacteriaceae, but Klebsiella species and Providencia stuartii were only inhibited by a high concentration of nalidixic acid.

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References

    1. Antimicrob Agents Chemother. 1982 Apr;21(4):670-2 - PubMed
    1. Antimicrob Agents Chemother. 1982 Jun;21(6):925-34 - PubMed
    1. J Antimicrob Chemother. 1982 Jul;10(1):25-30 - PubMed

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