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Clinical Trial
. 1983 Nov 17;12(41):2631-3.

[Intravenous administration of plasmin-treated immunoglobulins. A 2-year study in 16 patients with humoral deficiency]

[Article in French]
G Luzi, L Rosei, G P d'Offizi
  • PMID: 6228804
Clinical Trial

[Intravenous administration of plasmin-treated immunoglobulins. A 2-year study in 16 patients with humoral deficiency]

[Article in French]
G Luzi et al. Presse Med. .

Abstract

The immunological and clinical results of a 2-year study of 16 patients with agammaglobulinaemia (common variable in 12 and sex-linked in 4) are reported. Plasmin-treated immunoglobulins were injected at 3 weeks' intervals during the first part of the trial and at 2 weeks' interval during the second part. An increase in serum IgG levels was observed after 24 hours and 7 days, with progressive return to initial values on the 14th day. Twelve patients showed signs of clinical improvement.

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