Two-dimensional 1H NMR study of the lambda operator site OL1: a sequential assignment strategy and its application
- PMID: 6229791
- PMCID: PMC344624
- DOI: 10.1073/pnas.81.1.130
Two-dimensional 1H NMR study of the lambda operator site OL1: a sequential assignment strategy and its application
Abstract
The solution structure and dynamics of the 17-base-pair synthetic operator site OL1, which is recognized by the cI and Cro repressors of bacteriophage lambda, is studied by two-dimensional NMR methods. A sequential assignment strategy for nucleic acids is proposed and illustrated by the assignments of the base and sugar protons of OL1.
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