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. 1984 Mar;29(3):221-6.

The retinoids in acne

D E Bushnell, S Billstein, R A Schwartz, W C Lambert
  • PMID: 6230905

The retinoids in acne

D E Bushnell et al. Am Fam Physician. 1984 Mar.

Abstract

Vitamin A is essential for growth and development, reproduction and vision in humans. Chemical modification of vitamin A has yielded compounds showing therapeutic promise in skin and neoplastic diseases. The medicinal use of retinoids (vitamin A and its derivatives) is limited by the toxicity associated with this group of compounds. One retinoid, 13-cis-retinoic acid, has proved to be quite effective in the treatment of severe recalcitrant cystic acne under conditions in which toxicity is manageable.

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