Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Jan;40(1):6-11.

Theophylline bioavailability following oral administration of six sustained-release preparations

D L Spangler, D D Kalof, F L Bloom, H J Wittig
  • PMID: 623398

Theophylline bioavailability following oral administration of six sustained-release preparations

D L Spangler et al. Ann Allergy. 1978 Jan.

Abstract

Plasma theophylline concentrations were measured in 20 adults after single doses of 8 mg/kg of each of six oral sustained-release theophylline preparations. Twelve subjects were studied in a multiple-dose trial. Comparison of bioavailability and absorption characteristics suggest usefulness of some of these products for the purpose of maintaining safe and effective blood levels with twice-a-day dosing.

PubMed Disclaimer