[Behavior of blood values of prolactin, TSH, FSH, and LH in gastroduodenal ulcer during drug therapy]

Abstract

A study has been carried out on 20 male patients affected by gastric and duodenal ulcer disease and undergoing pharmacological treatment with pirenzepine, cimetidine, carbenoxolone and zolimidine in a multicentre controlled clinical trial, on PRL, TSH, FSH, LH plasma levels, taking into account the circadian rhythms of these endocrine variables. Basal and follow-up tests have been carried out, as well as a stimulation tests with TRH and LHRH. The findings do not allow for definite conclusions: two patients have shown moderate increases in the PRL levels after cimetidine; all patients have shown optimum responses to the stimulation test.