Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984 Jul 20;225(4659):324-6.
doi: 10.1126/science.6234658.

The structure of rat preproatrial natriuretic factor as defined by a complementary DNA clone

C E Seidman, A D Duby, E Choi, R M Graham, E Haber, C Homcy, J A Smith, J G Seidman

The structure of rat preproatrial natriuretic factor as defined by a complementary DNA clone

C E Seidman et al. Science. .

Abstract

The structure of rat preproatrial natriuretic factor ( preproANF ) was determined by nucleotide sequence analysis of an ANF complementary DNA clone. PreproANF is composed of a hydrophobic leader segment (20 amino acids), a precursor containing one glycosylation site (106 amino acids), and ANF (24 amino acids). Atrial natriuretic factor is located at the carboxyl terminus of the precursor molecule. The human, mouse, and rat genomes each contain a single ANF gene which is highly conserved.

PubMed Disclaimer

Publication types

Associated data

LinkOut - more resources