The inhibitory activity of a proline-rich polypeptide (PRP) on the immune response to polyvinylpyrrolidone (PVP)
- PMID: 6234865
Item in Clipboard
The inhibitory activity of a proline-rich polypeptide (PRP) on the immune response to polyvinylpyrrolidone (PVP)
Arch Immunol Ther Exp (Warsz).
1983.
Abstract
The effect of PRP on the humoral immune response to PVP was studied. It was found that PRP administered before immunization with PVP360 inhibits the immune response to this antigen. The studies revealed that PRP caused the increase of the activity of an "intrinsic" suppressor cells probably by enlarging the pool of these cells. PRP also increases generation of precursor cells for the "induced" suppressor category. The precursor cells are the targets for PVP25 giving rise to the antigen-specific, "induced" suppressor cells. The mechanism of the inhibitory action of PRP on the immune response to PVP is discussed.
Similar articles
-
The effect of a proline-rich polypeptide (PRP) on the humoral immune response. II. PRP induces differentiation of helper cells from glass-nonadherent thymocytes (NAT) and suppressor cells from glass-adherent thymocytes (GAT).Arch Immunol Ther Exp (Warsz). 1984;32(2):197-201. Arch Immunol Ther Exp (Warsz). 1984. PMID: 6237628
-
The effect of a proline-rich polypeptide (PRP) on the humoral immune response. I. Distinct effect of PRP on the T cell properties of mouse glass-nonadherent (NAT) and glass-adherent (GAT) thymocytes in thymectomized mice.Arch Immunol Ther Exp (Warsz). 1984;32(2):191-6. Arch Immunol Ther Exp (Warsz). 1984. PMID: 6333228
-
Proline-rich polypeptide from ovine colostrum: its effect on skin permeability and on the immune response.Immunology. 1979 Apr;36(4):875-81. Immunology. 1979. PMID: 437850 Free PMC article.
-
Proline-rich polypeptide (PRP)--an immunomodulatory peptide from ovine colostrum.Arch Immunol Ther Exp (Warsz). 1993;41(5-6):275-9. Arch Immunol Ther Exp (Warsz). 1993. PMID: 8010865 Review.
-
[Proline-rich-polypeptide from ovine colostrum (PRP): its structure and properties. II].Postepy Hig Med Dosw. 1988 May-Jun;42(3):237-59. Postepy Hig Med Dosw. 1988. PMID: 3073376 Review. Polish. No abstract available.
MeSH terms
Substances
LinkOut - more resources
Research Materials