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. 1984 Jul;35(7):436-42.
doi: 10.1177/000331978403500706.

The role of fibrinolysis in the therapy of peripheral vascular disease

C M Ambrus, J L Ambrus, H Gastpar, S D Sharma, O W Suh, R H Moore, P Williams

The role of fibrinolysis in the therapy of peripheral vascular disease

C M Ambrus et al. Angiology. 1984 Jul.

Abstract

In vivo thrombolytic studies in stumptailed monkeys indicated that pentoxifylline potentiates thrombolysis induced by urokinase activated human plasmin. Pentoxifylline as well as prostaglandin E1 released plasminogen activators and activated the fibrinolysin system. From this point of view pentoxifylline and prostaglandin E1 synergized with each other. Pentoxifylline potentiated the thrombolytic effect of prostaglandin E1 in vivo.

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