Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984 Oct;68(10):741-5.
doi: 10.1136/bjo.68.10.741.

Acute anterior uveitis, ankylosing spondylitis, back pain, and HLA-B27

A B Beckingsale, J Davies, J M Gibson, A R Rosenthal

Acute anterior uveitis, ankylosing spondylitis, back pain, and HLA-B27

A B Beckingsale et al. Br J Ophthalmol. 1984 Oct.

Abstract

One hundred and sixty-nine patients with acute anterior uveitis were studied for the presence of HLA-B27 tissue type, radiological evidence of ankylosing spondylitis, and a history of back pain. 60% were male; 45% were HLA-B27+. The male:female ratio in the HLA-B27+ group was the same as in the whole group. 24% had radiological evidence of ankylosing spondylitis, and, of these, 83% were HLA-B27+ while 17% were HLA-B27-. There was a definite correlation between the severity of the ankylosing spondylitis and preponderance of males in the HLA-B27+ group of patients. Significant back pain occurred in 60% of HLA-B27+ patients but in only 14% of HLA-B27- patients. The importance of the selection of patients and of consistency in the use of diagnostic criteria in studies relating to ankylosing spondylitis and acute anterior uveitis is stressed.

PubMed Disclaimer

References

    1. Lancet. 1974 Mar 16;1(7855):464 - PubMed
    1. Br J Ophthalmol. 1979 May;63(5):283-92 - PubMed
    1. Lancet. 1973 Nov 3;302(7836):994-6 - PubMed
    1. Scand J Rheumatol. 1980;9(4):234-6 - PubMed
    1. Radiology. 1976 May;119(2):293-7 - PubMed