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. 1984 Dec 21;12(24):9323-31.
doi: 10.1093/nar/12.24.9323.

Organization and structure of the mouse interleukin-2 gene

A Fuse, T Fujita, H Yasumitsu, N Kashima, K Hasegawa, T Taniguchi
Free PMC article

Organization and structure of the mouse interleukin-2 gene

A Fuse et al. Nucleic Acids Res. .
Free PMC article

Abstract

We have cloned a chromosomal DNA segment which covers the entire sequence for the murine interleukin-2 gene and analysed the structure of the gene. The coding regions are separated into four blocks by three introns each of which is located similarly to the corresponding human gene. The exon sequences can be aligned perfectly with the previously cloned cDNA sequence. Of particular interests is the presence of sequences within the 5'-flanking region which are highly conserved between mouse and man. The conserved region which spans more than 400 base pairs may play a role in the regulation of IL-2 gene expression.

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References

    1. Cell Immunol. 1983 Aug;80(1):1-9 - PubMed
    1. Nature. 1980 Jan 10;283(5743):220-4 - PubMed
    1. Nucleic Acids Res. 1982 Feb 11;10(3):967-77 - PubMed
    1. Nature. 1981 May 28;291(5813):335-8 - PubMed
    1. Nature. 1983 Mar 24-30;302(5906):305-10 - PubMed

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