Case Reports
doi: 10.1001/archneur.1980.00500530077013.
Pathogenesis of varicella-zoster angiitis in the CNS
- PMID: 6244805
- DOI: 10.1001/archneur.1980.00500530077013
Item in Clipboard
Case Reports
Pathogenesis of varicella-zoster angiitis in the CNS
Arch Neurol.
1980 Apr.
Abstract
A 20-year-old man with Hodgkin's disease experienced ophthalmic zoster with dissemination and CNS involvement. At autopsy, he was found to have granulomatous angiitis involving the basilar artery, and electron microscopy revealed virus-like particles in the outer layers of the vessel walls, but not the endothelium. This suggests that granulomatous angiitis of the CNS in varicella-zoster infections results from direct viral invasion of blood vessels, perhaps by contiguous spread from cranial nerves.
Similar articles
-
Subarachnoid hemorrhage and granulomatous angiitis of the basilar artery: demonstration of the varicella-zoster-virus in the basilar artery lesions.Stroke. 1986 Sep-Oct;17(5):1024-8. doi: 10.1161/01.str.17.5.1024. Stroke. 1986. PMID: 3020742
-
Hodgkin's disease and granulomatous angiitis of the central nervous system.Cancer. 1976 Nov;38(5):2027-32. doi: 10.1002/1097-0142(197611)38:5<2027::aid-cncr2820380527>3.0.co;2-h. Cancer. 1976. PMID: 186177
-
[Granulomatous angiitis of the basilar artery related to herpes zoster of the 7th cranial nerve].Neurologia. 1990 Mar;5(3):98-101. Neurologia. 1990. PMID: 2361047 Spanish.
-
Varicella-zoster virus: a re-emerging infection.J Investig Dermatol Symp Proc. 2001 Dec;6(3):183-7. doi: 10.1046/j.0022-202x.2001.00041.x. J Investig Dermatol Symp Proc. 2001. PMID: 11924825 Review.
-
Varicella zoster virus vasculopathy: The expanding clinical spectrum and pathogenesis.J Neuroimmunol. 2017 Jul 15;308:112-117. doi: 10.1016/j.jneuroim.2017.03.014. Epub 2017 Mar 18. J Neuroimmunol. 2017. PMID: 28335992 Free PMC article. Review.
Cited by
-
Herpes zoster and its neurological complications.Postgrad Med J. 1987 Feb;63(736):85-9. doi: 10.1136/pgmj.63.736.85. Postgrad Med J. 1987. PMID: 3671248 Free PMC article.
-
Ependymitis, leukoencephalitis, hydrocephalus, and thrombotic vasculitis following chronic infection by mouse hepatitis virus 3 (MHV 3).Acta Neuropathol. 1982;58(3):168-76. doi: 10.1007/BF00690797. Acta Neuropathol. 1982. PMID: 6297223 Free PMC article.
-
Association of herpes zoster vaccination and cardiovascular risk in patients with diabetes: long-term insights from a retrospective cohort study.BMJ Open. 2025 Feb 18;15(2):e090428. doi: 10.1136/bmjopen-2024-090428. BMJ Open. 2025. PMID: 39965942 Free PMC article.
-
Pediatric stroke: the importance of cerebral arteriopathy and vascular malformations.Childs Nerv Syst. 2010 Oct;26(10):1263-73. doi: 10.1007/s00381-010-1208-9. Epub 2010 Jul 13. Childs Nerv Syst. 2010. PMID: 20625743 Free PMC article. Review.
-
Varicella-Zoster Virus Vasculopathy: A Case Report Demonstrating Vasculitis using Black-Blood MRI.J Neurol Neurophysiol. 2015 Dec;6(6):1000342. doi: 10.4172/2155-9562.1000342. Epub 2015 Dec 28. J Neurol Neurophysiol. 2015. PMID: 27065314 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
