Viable deletion mutant in the medium and large T-antigen-coding sequences of the polyoma virus genome
- PMID: 6245272
- PMCID: PMC288657
- DOI: 10.1128/JVI.33.3.1215-1220.1980
Viable deletion mutant in the medium and large T-antigen-coding sequences of the polyoma virus genome
Abstract
A polyoma virus mutant that maps in the early region between the known hr-t and ts-a mutants has been isolated. Its 66-base-pair deletion results in structural changes in both medium and large T-antigens but causes no substantial alterations in viral replication or cell transformation.
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