Role of two particle types in bovine rotavirus morphogenesis
- PMID: 6246258
- PMCID: PMC288694
- DOI: 10.1128/JVI.34.1.272-276.1980
Role of two particle types in bovine rotavirus morphogenesis
Abstract
The involvement of light (L) and dense (D) bovine rotavirus particle types during virus replication has been studied. It was found that infectious parental L virions are uncoated in vivo to a particle similar to native D particles. Differences in the rate of synthesis and relative yields of L and D particles in MDBK and MA-104 cells have been detected. Results from pulse-chase labeling experiments indicate that D particles serve as morphogenic precursors to the complete L virion.
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