Mouse-killing in rats induces a naloxone-blockable increase in nociceptive threshold
- PMID: 6247166
- DOI: 10.1016/0014-2999(80)90445-8
Mouse-killing in rats induces a naloxone-blockable increase in nociceptive threshold
Abstract
Mouse-killing behaviour in rats increased the nociceptive threshold for paw licking, as measured in the hot-plate test. This effect was prevented by the opiate antagonist naloxone, which, on the other hand, had no influence on mouse-killing behavior per se. It is concluded that opioid mechanisms may be involved in changes of nociceptive threshold associated with aggressive behavior.
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