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. 1980 Mar;27(3):897-902.
doi: 10.1128/iai.27.3.897-902.1980.

Curing of a plasmid is correlated with an attenuation of virulence in the marine fish pathogen Vibrio anguillarum

Curing of a plasmid is correlated with an attenuation of virulence in the marine fish pathogen Vibrio anguillarum

J H Crosa et al. Infect Immun. 1980 Mar.

Abstract

The transposon A sequence Tn1 containing the ampicillin resistance determinants was transposed from RP4 to a plasmid of the marine fish pathogen Vibrio anguillarum. Curing experiments in which plasmid loss was determined by analysis of the segregation of the ampicillin resistance phenotype showed the association of virulence with the specific V. anguillarum plasmid class.

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