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. 1980 Jul;4(7):641-8.
doi: 10.1016/0309-1651(80)90202-7.

Immunohistochemical localization of cyclic AMP, cyclic GMP and calmodulin in Dictyostelium discoideum

J M Mato, A L Steiner

Immunohistochemical localization of cyclic AMP, cyclic GMP and calmodulin in Dictyostelium discoideum

J M Mato et al. Cell Biol Int Rep. 1980 Jul.

Abstract

Using an indirect immunofluorescence technique cyclic AMP, cyclic GMP and calmodulin have been localized in Dictyostelium discoideum cells. The bound cyclic AMP is localized throughout the cell. Cyclic GMP and calmodulin are markedly localized in the nuclear area of the cell. No changes in the pattern of staining was observed during differentiation. Chemotactic stimulation induced a transient increase of cyclic GMP staining.

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