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. 1980 Sep 19;209(4463):1380-4.
doi: 10.1126/science.6251545.

Recombination of dispersed repeated DNA sequences in yeast

S Scherer, R W Davis

Recombination of dispersed repeated DNA sequences in yeast

S Scherer et al. Science. .

Abstract

Yeast transformation can be used to insert new sequence arrangements into a variety of chromosomal locations by homologous recombination. These newly inserted sequences can recombine with similar sequences located on other chromosomes. In these events, information is duplicated without being lost at the site from which it is derived. Similar mechanisms might be utilized by cells to provide new functions during development or differentiation.

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