The role of adjuvant therapy in Stage I ovarian cancer
- PMID: 6252780
- DOI: 10.1016/0002-9378(80)90024-1
The role of adjuvant therapy in Stage I ovarian cancer
Abstract
Women with Stage I epithelial carcinoma of the ovary were initially treated by an extirpative operation and were subsequently randomized to either no further treatment, radiotherapy, or chemotherapy. Only two patients (6%) treated with chemotherapy developed recurrence, compared to five (17%) and seven (30%) patients in the no-treatment and radiotherapy regimens, respectively (P < 0.05). All patients, with the possible exception of those with Stage IA(1)g1, appeared to benefit from adjuvant chemotherapy compared to no treatment or radiotherapy.
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