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Clinical Trial
. 1980 Sep 15;138(2):139-45.
doi: 10.1016/0002-9378(80)90024-1.

The role of adjuvant therapy in Stage I ovarian cancer

Clinical Trial

The role of adjuvant therapy in Stage I ovarian cancer

M M Hreshchyshyn et al. Am J Obstet Gynecol. .

Abstract

Women with Stage I epithelial carcinoma of the ovary were initially treated by an extirpative operation and were subsequently randomized to either no further treatment, radiotherapy, or chemotherapy. Only two patients (6%) treated with chemotherapy developed recurrence, compared to five (17%) and seven (30%) patients in the no-treatment and radiotherapy regimens, respectively (P < 0.05). All patients, with the possible exception of those with Stage IA(1)g1, appeared to benefit from adjuvant chemotherapy compared to no treatment or radiotherapy.

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