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. 1976;17(2):177-84.

[Histamine liberation in extracorporeal circulation]

[Article in French]
  • PMID: 62533

[Histamine liberation in extracorporeal circulation]

[Article in French]
B Thirion et al. Ann Anesthesiol Fr. 1976.

Abstract

Extra-corporeal circulation (E.C.C.) has been held responsible for histamine liberation incidents, essentially by a mechanical cause. In order to prove this, the authors assayed the overall histaminaemia at different times during E.C.C. in 11 patients. The results are discussed in terms of the patients' backgrounds, temperature, hematocrit, blood gases and the acid-base balance, and electrolyte balance. Histaminaemia, corrected depending on the dilution, did not show any significant variation, even in two patients who clinically had anaphylactic manifestations.

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