[The radiation dose to children bone scintigraphy with 99mTc-phosphate compounds (author's transl)]

Abstract

In order to determine the radiation dose to children during bone scintigraphy, distribution and excretion measurements on 99mTc-pyrophosphate and 99mTc-diphosphonate were carried out in rats, piglets, children and adults. Because of the more intensive bone metabolism in children, uptake of 43 to 47% is higher than in adults, in whom uptake in the skeleton reaches 33 to 36%. Assuming homogenous distribution of uptake, radiation dose to the skeleton in children of the ages investigated was 51 to 55 mrd per mCi. Bearing in mind the non-homogeneous distribution in the juvenile skeleton, radiation dose at growth point reaches 85 to 95 mrd per mCi.