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. 1980 Sep;29(3):972-80.
doi: 10.1128/iai.29.3.972-980.1980.

Detection and quantification of type C viral proteins in tissues and sera with an enzyme immunoassay

H Schetters, R Hehlmann, V Erfle, M Ramanarayanan

Detection and quantification of type C viral proteins in tissues and sera with an enzyme immunoassay

H Schetters et al. Infect Immun. 1980 Sep.

Abstract

The detection and quantification of retroviral proteins in cells, tumors, and sera by an enzyme immunoassay technique (enzyme-linked immunosorbent assay [ELISA]) is described. The ELISA technique has been applied to three viral systems: murine leukemia virus, baboon endogenous virus, and simian sarcoma virus. By detecting 0.1 nf of retroviral antigen, the sensitivity of the ELISA is comparable to that of the competition radioimmunoassay technique.

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