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. 1980 Sep 18;287(5779):203-8.
doi: 10.1038/287203a0.

DNA N-glycosylases and UV repair

B Demple, S Linn

DNA N-glycosylases and UV repair

B Demple et al. Nature. .

Abstract

Repair of some DNA photoproducts can be mediated by glycosylic bond hydrolysis. Thus, Escherichia coli endonuclease III releases 5,6-hydrated thymines as free bases, while T4 UV endonuclease releases one of two glycosylic bonds holding pyrimidine dimers in DNA. In contrast, uninfected E. coli apparently does not excise pyrimidine dimers via a DNA glycosylase.

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