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Comparative Study
. 1980 Aug 25;8(16):3659-72.
doi: 10.1093/nar/8.16.3659.

Secondary structures for splice junctions in eukaryotic and viral messenger RNA precursors

B C Trapnell, P Tolstoshev, R G Crystal
Free PMC article
Comparative Study

Secondary structures for splice junctions in eukaryotic and viral messenger RNA precursors

B C Trapnell et al. Nucleic Acids Res. .
Free PMC article

Abstract

Thermodynamically stable secondary structures have been found for adjacent splice junctions of 17 introns from 10 eukaryotic and viral mRNA precursors. Complementary regions in these structures position the exons to be ligated in a favourable orientation for splicing. The possible role of these structures in a general splicing mechanism in described.

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