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. 1980 Oct;21(3):647-51.
doi: 10.1016/0092-8674(80)90428-6.

The nucleotide sequence of the human beta-globin gene

R M Lawn, A Efstratiadis, C O'Connell, T Maniatis

The nucleotide sequence of the human beta-globin gene

R M Lawn et al. Cell. 1980 Oct.

Abstract

We report the complete nucleotide sequence of the human beta-globin gene. The purpose of this study is to obtain information necessary to study the evolutionary relationships between members of the human beta-like globin gene family and to provide the basis for comparing normal beta-globin genes with those obtained from the DNA of individuals with genetic defects in hemoglobin expression.

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