Modification of radiation response by agents that elevate the intracellular c-AMP level
- PMID: 6254799
- DOI: 10.1007/BF01953816
Modification of radiation response by agents that elevate the intracellular c-AMP level
Abstract
A study has been made of the effects of drugs known to elevate c-AMP level on radiation-induced damage in thymocytes. The test used was the ability of the cells to exclude dye, beta-receptor stimulation and phosphodiesterase inhibition were found to induce radioresistance. The possible importance of the plasma membrane in connection with cytoplasmic factors is briefly discussed.
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