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. 1980 Dec;144(3):1200-2.
doi: 10.1128/jb.144.3.1200-1202.1980.

Genetic behavior of the methicillin resistance determinant in Staphylococcus aureus

G C Stewart, E D Rosenblum

Genetic behavior of the methicillin resistance determinant in Staphylococcus aureus

G C Stewart et al. J Bacteriol. 1980 Dec.

Abstract

The cotransformation frequency of mecC5 with pur-102 using Staphylococcus aureus C5 deoxyribonucleic acid was found to be approximately 45%. However, in cotransduction studies, there was a 15% cotransduction of purine prototrophy and methicillin sensitivity but, in the reciprocal cross, no purine-prototrophic plus Mecr cotransductants were obtained (frequency less than 0.06%). The data support the hypothesis that the mec determinant resides on an inserted deoxyribonucleic acid sequence in S. aureus and that there is no allelic equivalent in sensitive cells.

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References

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