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. 1981 Jan 1;289(5793):33-7.
doi: 10.1038/289033a0.

Isolation of a gene from Drosophila by complementation in yeast

S Henikoff, K Tatchell, B D Hall, K A Nasmyth

Isolation of a gene from Drosophila by complementation in yeast

S Henikoff et al. Nature. .

Abstract

Transformation of mutant yeast cells by cloned genomic DNA from a higher eukaryote has made it possible to isolate a Drosophila DNA sequence that complements a yeast adenine-8-mutation. A 0.8-kilobase poly(A)-containing RNA is transcribed from the cloned Drosophila segment in transformed yeast cells and can account for functional expression of the gene.

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