[Susceptibility of anaerobic bacteria to cefoxitin (author's transl)]

Abstract

Nine strains of Clostridium perfringens type A and 10 strains of Bacteroïdes fragilis s. spec. fragilis, recently isolated from blood culture, were tested for their cefoxitin susceptibility. The MIC for Clostridium perfringens ranged from 0,6 to 5 mg/l and 1,2 to 10 mg/l for Bacteroïdes fragilis. In most cases, the MBC were identical with the MIC for Clostridium perfringens, but for Bact. frag. there was a difference of 2 dilutions in their MBC. Cefoxitin activity was not modified by a variation in inoculum density.