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. 1980 Dec;22(3):787-97.
doi: 10.1016/0092-8674(80)90555-3.

Identification of a functional promoter in the long terminal repeat of Rous sarcoma virus

T Yamamoto, B de Crombrugghe, I Pastan

Identification of a functional promoter in the long terminal repeat of Rous sarcoma virus

T Yamamoto et al. Cell. 1980 Dec.

Abstract

Specific initiation of transcription of Rous sarcoma virus by RNA polymerase II was obtained in a cell-free system using cloned RSV DNA as template. The site of initiation is located in the common "C" region of the long terminal repeat (LTR), 23 bp downstream from the promoter-like sequence TATTTAAG. This finding indicates that the basic information necessary for RSV transcription lies within the viral genome.

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