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. 1980 Dec;36(3):872-7.
doi: 10.1128/JVI.36.3.872-877.1980.

Structure of and alterations to defective murine sarcoma virus particles lacking envelope proteins and core polyprotein cleavage

A Demsey, F Collins, D Kawka

Structure of and alterations to defective murine sarcoma virus particles lacking envelope proteins and core polyprotein cleavage

A Demsey et al. J Virol. 1980 Dec.

Abstract

HTG2 hamster cells produce a defective murine sarcoma virus lacking gp70 and, consequently, viral surface projections (knobs), but the lack of knobs appears to have no effect on intramembrane particle distribution. In addition, it has been noted that the core of the virus remains in the "immature" form as a result of the failure of the polyprotein precursor (p65) to undergo cleavage. However, incubation of HTG2 virus with avian myoblastosis virus was found to yield specific cleavage products of p65.

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References

    1. Virology. 1974 Jan;57(1):287-90 - PubMed
    1. Curr Top Microbiol Immunol. 1974;(68):29-58 - PubMed
    1. Virology. 1975 Jul;66(1):253-60 - PubMed
    1. Curr Top Microbiol Immunol. 1975;70:1-30 - PubMed
    1. J Virol. 1977 Jan;21(1):358-65 - PubMed

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