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. 1980:358:138-48.
doi: 10.1111/j.1749-6632.1980.tb15392.x.

Ion pathways in proteins of the sarcoplasmic reticulum

D H MacLennan, R A Reithmeier, V Shoshan, K P Campbell, D LeBel, T R Herrmann, A E Shamoo

Ion pathways in proteins of the sarcoplasmic reticulum

D H MacLennan et al. Ann N Y Acad Sci. 1980.

Abstract

In summary, we have begun to characterize three different ion pathways in the sarcoplasmic reticulum. Ca2+-ionophoric activity has been traced to a 13,000-dalton CNBr fragment localized at the amino terminus of the ATPase molecule... The pathway involved in Ca2+ release can be distinguished from the pathway involved in Ca2+ uptake by its insensitivity to quercetin. An anion pathway is sensitive to DIDS and appears to be localized in the ATPase molecule

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