doi: 10.1111/j.1651-2227.1978.tb16299.x.
Brain-typical creatinekinase in the serum of newborn infants with perinatal brain damage
- PMID: 626076
- DOI: 10.1111/j.1651-2227.1978.tb16299.x
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Brain-typical creatinekinase in the serum of newborn infants with perinatal brain damage
Acta Paediatr Scand.
1978 Mar.
Abstract
The normal values of serum-CK-activity in healthy newborns varied greatly (95% range: 4--165 U/l; 257 probands) and the borderline to pathological values was not sharp. Brain-typical CK-isoenzyme (CK-BB) could be detected in serum of 6 of 8 infants with perinatal brain damage by means of agar gel electrophoresis. The combination of neuropathological symptoms, increased total-serum-CK-activity, and significant amount of CK-BB in serum seemed to be a sure sign of severe CNS-damage in newborns.
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