Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1980 Dec 15;192(3):947-50.
doi: 10.1042/bj1920947.

Ontogenic development of alpha-adrenergic receptors and responsiveness in white adipocytes

R Pecquery, Y Giudicelli

Ontogenic development of alpha-adrenergic receptors and responsiveness in white adipocytes

R Pecquery et al. Biochem J. .

Abstract

The influence of age on adipocyte alpha-adrenergic receptors was studied by using the binding of [3H]dihydroergocryptine to crude adipocyte membranes from hamsters of different ages (1-10 months). The number of alpha-receptor sites was found to increase with increasing age, but in contrast, their binding affinity remained unchanged. These changes in receptor concentrations, which were not related to cell-size differences, were also accompanied by parallel variations of the alpha-adrenergic responsiveness of the fat-cells.

PubMed Disclaimer

References

    1. J Clin Invest. 1970 Jun;49(6):1213-23 - PubMed
    1. J Gerontol. 1971 Jan;26(1):8-12 - PubMed
    1. J Lipid Res. 1971 Jan;12(1):91-5 - PubMed
    1. Biochim Biophys Acta. 1971 Apr 13;233(2):334-47 - PubMed
    1. Biochem J. 1971 Feb;121(3):561-2 - PubMed

Publication types