Calcium channels in the somatic membrane of the rat dorsal root ganglion neurons, effect of cAMP
- PMID: 6263419
- DOI: 10.1016/0006-8993(81)90457-1
Calcium channels in the somatic membrane of the rat dorsal root ganglion neurons, effect of cAMP
Abstract
Isolated rat dorsal root ganglion neurons have been perfused with potassium-free solutions containing cAMP, ATP and Mg2+ ions. In these conditions stable inward calcium currents can be recorded in the somatic membrane of all investigated cells. The kinetics of these currents can be approximated by a modified Hodgkin-Huxley equation using a square power of the m-variable; its inactivation is extremely slow. The corresponding channels pass Ba2+ ions about twice more effective than Ca2+.
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