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. 1981 Jun 9;214(1):210-4.
doi: 10.1016/0006-8993(81)90457-1.

Calcium channels in the somatic membrane of the rat dorsal root ganglion neurons, effect of cAMP

Calcium channels in the somatic membrane of the rat dorsal root ganglion neurons, effect of cAMP

S A Fedulova et al. Brain Res. .

Abstract

Isolated rat dorsal root ganglion neurons have been perfused with potassium-free solutions containing cAMP, ATP and Mg2+ ions. In these conditions stable inward calcium currents can be recorded in the somatic membrane of all investigated cells. The kinetics of these currents can be approximated by a modified Hodgkin-Huxley equation using a square power of the m-variable; its inactivation is extremely slow. The corresponding channels pass Ba2+ ions about twice more effective than Ca2+.

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