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. 1981 Apr;11(1-2):125-8.
doi: 10.1007/BF01991480.

Analysis of histamine actions by intra- and extracellular recording in hippocampal slices of the rat

H L Haas

Analysis of histamine actions by intra- and extracellular recording in hippocampal slices of the rat

H L Haas. Agents Actions. 1981 Apr.

Abstract

Extra- and intracellular recordings from CA1 pyramidal and dentate granule cells in hippocampal slices of the rat revealed a depressant effect of histamine which was usually accompanied by a hyperpolarization but no changes in conductance of the cell membrane. Synaptic potentials were unaffected. It is concluded that histamine has a post-synaptic action on ionic conductance in the dendrites, that allows a modulation of quick information transfer but no rapid synaptic transmission.

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References

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