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. 1981 Aug 21;213(4510):928-30.
doi: 10.1126/science.6266017.

Opioid inhibition of dopamine release from nervous tissue of Mytilus edulis and Octopus bimaculatus

Opioid inhibition of dopamine release from nervous tissue of Mytilus edulis and Octopus bimaculatus

G B Stefano et al. Science. .

Abstract

Morphine and D-Ala2-Met-enkephalin as well as other opioids suppress potassium-stimulated release of 3H-labeled dopamine from neurons tissue of two marine invertebrates, Mytilus edulis and Octopus bimaculatus. Naloxone reverses the inhibitory effects in both species. Potassium-stimulated release of 3H-labeled serotonin is not altered by opioids. It is postulated that opiate receptors and their endogenous effectors play a prominent role in regulation of transmitter release in invertebrates.

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