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. 1981 Jun 25;9(12):2753-9.
doi: 10.1093/nar/9.12.2753.

DNA methyltransferases affecting the sequence 5'CCGG

Free PMC article

DNA methyltransferases affecting the sequence 5'CCGG

S Jentsch et al. Nucleic Acids Res. .
Free PMC article

Abstract

B. subtilis phage SPbeta and Moraxella sp. code for DNA methyltransferases which methylate both cytosines of the sequence 5'CCGG. Experiments using a B. subtilis strain whose DNA is sensitive to HpaII and resistant to MspI degradation, indicated that methylation of the outer C of this sequence provides protection against the restriction enzyme MspI.

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