DNA methyltransferases affecting the sequence 5'CCGG
- PMID: 6269059
- PMCID: PMC326890
- DOI: 10.1093/nar/9.12.2753
DNA methyltransferases affecting the sequence 5'CCGG
Abstract
B. subtilis phage SPbeta and Moraxella sp. code for DNA methyltransferases which methylate both cytosines of the sequence 5'CCGG. Experiments using a B. subtilis strain whose DNA is sensitive to HpaII and resistant to MspI degradation, indicated that methylation of the outer C of this sequence provides protection against the restriction enzyme MspI.
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